|
T1154 |
Rifaximin
|
|
DNA/RNA Synthesis
,
Antibacterial
,
Antibiotic
|
|
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting... |
|
T1305 |
Ceftazidime
|
GR20263 |
Antibacterial
,
Antibiotic
|
|
Ceftazidime (GR20263) is a beta-lactam, cephalosporin antibiotic with bactericidal activity. |
|
T6582 |
Mezlocillin Sodium
|
Baycipen |
Antibacterial
,
Antibiotic
|
|
Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. |
|
T20525 |
Chloramphenicol palmitate
|
|
Antibacterial
,
Antibiotic
|
|
Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra... |
|
T0234 |
Methicillin sodium salt
|
Methicillin sodium,Meticillin sodium |
Antibacterial
,
Antibiotic
|
|
Methicillin sodium salt is the sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. |
|
T1444 |
Lomefloxacin
|
SC47111A |
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity. |
|
T60050 |
ANT3310
|
|
Antibacterial
|
|
ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection. |
|
T35427 |
β-Lactamase-IN-2
|
|
Antibacterial
|
|
β-Lactamase-IN-2 is an inhibitor of β-Lactamase with anti-microbial and anti-bacterial effects. |
|
T0748 |
Sulfameter
|
5-Methoxysulfadiazine,Sulfametoxydiazine |
DHFR
,
Antibacterial
,
Antibiotic
|
|
Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy. |
|
T0328 |
Hexetidine
|
NSC-17764 |
Antibacterial
,
Antifungal
|
|
Hexetidine (NSC-17764) is a bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene. |
|
T0830 |
Bithionol
|
Actamer |
cAMP
,
Parasite
|
|
Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bit... |
|
T1647 |
Ronidazole
|
Ronidazol,Ridzol |
Antibacterial
,
Antibiotic
,
Parasite
|
|
Ronidazole (Ronidazol) is an antiprotozoal and antimicrobial agent used mainly in veterinary practice. |
|
T1070 |
Cefmetazole sodium
|
Sodium cefmetazole |
Antibacterial
,
Antibiotic
|
|
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types... |
|
T37340 |
N4-Acetylsulfamethoxazole
|
N-acetyl Sulfamethoxazole |
Others
|
|
N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be detected in urine. |
|
T3279 |
Silver sulfadiazine
|
Silvadene,Dermazin,Flamazine |
DNA/RNA Synthesis
,
Antibacterial
,
Antibiotic
|
|
Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity. |
|
T15394 |
Glyceryl monocaprate
|
2,3-Dihydroxypropyl decanoate,DECANOIN,Monocaprin |
Antibacterial
,
HSV
|
|
Glyceryl monocaprate (2,3-Dihydroxypropyl decanoate) has inhibitory effect on Herpes Simplex Virus (HSV). It also offers an effective treatment for herpes labialiss. Glyceryl monocaprate is a capric acid against 1-monogl... |
|
T6349 |
Sitafloxacin Hydrate
|
DU-6859a,DU6859a hydrate |
Antibacterial
,
Antibiotic
|
|
Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. |
|
T1625 |
Lomefloxacin hydrochloride
|
Lomefloxacin HCl,Okacyn,Maxaquin |
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during... |
|
T1557 |
Acetylspiramycin
|
Spiramycin II,Foromacidin B,ASPM,Spiramycin B |
ribosome
,
Antibacterial
,
Antibiotic
|
|
Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis. |
|
T8139 |
Sulfamethoxazole sodium
|
Ro 4-2130 sodium |
Others
,
Antibacterial
,
Antibiotic
|
|
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic |
|
T7387 |
Ceftaroline fosamil
|
TAK-599,PPI0903 |
Antibacterial
,
Antibiotic
|
|
Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens. |
|
T4991 |
Ertapenem sodium
|
MK-826,L-749345 |
Antibacterial
,
Antibiotic
|
|
Ertapenem sodium (MK-826) is a new long-acting 1-β-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with extended-spectrum β-lactamases. |
|
T1101 |
Minocycline hydrochloride
|
Minocycline HCl |
HIF/HIF Prolyl-Hydroxylase
,
Antibacterial
,
Antibiotic
|
|
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor... |
|
T22287 |
Cefteram pivoxil
|
Ro 19-5248,T-2588 |
Antibacterial
,
Antibiotic
|
|
Cefteram pivoxil (T-2588) (CFTM-PI) is an oral antibiotic available in powder suspension and tablet formulations indicated in China for the treatment of bacterial infections. |
|
T6415 |
Bismuth Subcitrate Potassium
|
|
Others
,
Antibacterial
,
Antibiotic
|
|
Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection. |
|
T26717 |
AZD-5099
|
AZD5099 |
|
|
AZD-5099 is a DNA gyrase modulator potentially for the treatment of bacterial infection. |
|
T13667L |
Dusquetide
|
SGX942 |
Others
|
|
Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection. |
|
T37912 |
Furanone C-30
|
|
|
|
Synthetic furanone bacterial quorum sensing inhibitor. Inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Also inhibits bacterial quorum sensing... |
|
T61581 |
LasR-IN-2
|
|
|
|
LasR-IN-2, a compound that inhibits the activity of LasR, forms hydrogen bonding with the TRY-56 residue. It finds application in the study of bacterial infection, neutropenia, severe burns, and chronic lung disease in c... |
|
T80630 |
H-Arg-OtBu dihydrochloride
|
|
Antibiotic
|
|
H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial that engages the negatively charged bacterial membrane through electrostatic and hydrophobic interactions, with applications in bacterial infection disea... |
|
T1405L |
Cefditoren sodium
|
Cefditoren pivoxil,Cefditoren,ME-1206,ME1206,ME 1206 |
|
|
Cefditoren sodium is a cephalosporin antibiotic potentially for the treatment of bacterial infection. The expression levels of Mrp2, Bcrp, Oat2 mRNA were markedly increased, while P-gp and Oct1 mRNA were decreased. In co... |
|
T79396 |
T3SS-IN-2
|
|
|
|
T3SS-IN-2 (Compound 2h) serves as an inhibitor of the type three secretion system (T3SS), with applications in bacterial infection research [1]. |
|
T15734 |
Lenampicillin hydrochloride
|
KBT 1585 hydrochloride |
Antibacterial
|
|
Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the... |
|
T70268 |
3A-MPLA
|
|
|
|
Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tu... |
|
T75300 |
Cefazolin sodium pentahydrate
|
|
|
|
Cefazolin sodium pentahydrate, a first-generation cephalosporin antibiotic, is employed in diverse bacterial infection research [1] and exhibits an anti-inflammatory effect capable of attenuating post-operative cognitive... |
|
T69350 |
Ethionamide HCl
|
|
|
|
Ethionamide HCl is the salt form of Ethionamide, a second-line antitubercular agent that inhibits mycolic acid synthesis. Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis.... |
|
T74998 |
LmNADK1-IN-1
|
|
|
|
LmNADK1-IN-1 (compound MC1) is an inhibitor of nicotinamide adenine dinucleotide kinases ( NADK1 ) from L. monocytogenes with a K i value of 54 nM. LmNADK1-IN-1 can be used for the research of bacterial infection [1] . |
|
T79387 |
YJ182
|
|
|
|
YJ182 is an NDM-1 inhibitor with an IC50 of 0.23 μM, and additionally inhibits IMP-1, VIM-2, GIM-1, and MMP-2 with respective IC50 values of 0.25, 0.61, 0.49, and 6.92 μM. It is utilized in bacterial infection research [... |
|
T36357 |
Dimethyldioctadecylammonium (bromide)
|
|
|
|
Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune ... |
|
T76227 |
LS-BF1
|
|
|
|
LS-BF1, a stable and low-toxicity cationic antimicrobial peptide, exhibits broad-spectrum antibacterial activity that encompasses the notorious ESKAPE pathogens through a cell membrane disruption mechanism. The compound ... |
|
T35701 |
FSL-1 TFA
|
|
|
|
FSL-1 TFA, a toll-like receptor 2/6 (TLR2/6) agonist derived from bacteria, bolsters resistance against experimental HSV-2 infection[1] and stimulates MMP-9 production via the TLR2 and NF-κB/AP-1 signaling pathways in mo... |
|
T83849 |
OP-145 TFA
|
acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide,P60.4-Ac |
|
|
OP-145, a derivative of the antimicrobial peptide LL-37, is a synthetic antimicrobial peptide showing activity against E. coli, P. aeruginosa, C. albicans, and A. niger, with minimum inhibitory concentrations (MICs) of 2... |
|
T38042 |
Resolvin D4
|
Resolvin D4,RvD4 |
|
|
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreat... |
|
T36021 |
Flumequine-13C3
|
Flumequine-13C3 |
|
|
Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. col... |
|
T37250 |
Cefazolin-13C2,15N
|
Cefazolin-13C2,15N |
|
|
Cefazolin-13C2,15N is intended for use as an internal standard for the quantification of cefazolin by GC- or LC-MS. Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-posi... |
|
T83735 |
Pap12-6 TFA
|
|
|
|
Pap12-6, an antibacterial peptide originating from the first twelve N-terminal amino acids of papiliocin found in P. xuthus larvae, exhibits activity against a range of eight Gram-negative bacteria (e.g., E. coli, P. aer... |
